Bennett-Sub

Publications

2017

In vivo mapping of tissue- and subcellular-specific proteomes in Caenorhabditis elegans.
Reinke AW, Mak R, Troemel ER, Bennett EJ.
Sci Adv. 2017 May 10;3(5)
PMID: 28508060

ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation.
Sundaramoorthy E, Leonard M, Mak R, Liao J, Fulzele A, Bennett EJ.
Mol Cell. 2017 Feb 16;65(4):751-760.
PMID: 28132843

Biallelic mutations in the 3′ exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing.
Lardelli RM, Schaffer AE, Eggens VR, Zaki MS, Grainger S, Sathe S, Van Nostrand EL, Schlachetzki Z, Rosti B, Akizu N, Scott E, Silhavy JL, Heckman LD, Rosti RO, Dikoglu E, Gregor A, Guemez-Gamboa A, Musaev D, Mande R, Widjaja A, Shaw TL, Markmiller S, Marin-Valencia I, Davies JH, de Meirleir L, Kayserili H, Altunoglu U, Freckmann ML, Warwick L, Chitayat D, Blaser S, Çağlayan AO, Bilguvar K, Per H, Fagerberg C, Christesen HT, Kibaek M, Aldinger KA, Manchester D, Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi NC, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Nassogne MC, Bennett EJ, Yeo GW, Baas F, Lykke-Andersen J, Gleeson JG.
Nat Genet. 2017 Jan 16.
PMID: 28092684

A “Retrochaperone” Function for Cdc48: the Cdc48 Complex is Required for Retrotranslocated ERAD-M Substrate Solubility.
Neal SE, Mak R, Bennett EJ, Hampton R.
J Biol Chem. 2017 Jan 11.
PMID: 28077573

Identification of microsporidia host-exposed proteins reveals a repertoire of rapidly evolving proteins.
Reinke AW, Balla KM, Bennett EJ, Troemel ER.
Nat Commun. 2017 Jan 9;8:14023.
PMID: 28067236

2016

Proteome complexity and the forces that drive proteome imbalance.
Harper JW, Bennett EJ.
Nature. 2016 Sep 14;537(7620):328-38.
PMID: 27629639

The C-Terminal RGG Domain of Human Lsm4 Promotes Processing Body Formation Stimulated by Arginine Dimethylation.
Arribas-Layton M, Dennis J, Bennett EJ, Damgaard CK, Lykke-Andersen J.
Mol Cell Biol. 2016 Aug 12;36(17):2226-35. doi: 10.1128/MCB.01102-15. Print 2016 Sep 1.
PMID: 27247266

Using the Ubiquitin-modified Proteome to Monitor Distinct and Spatially Restricted Protein Homeostasis Dysfunction.
Gendron JM, Webb K, Yang B, Rising L, Zuzow N, Bennett EJ.
Mol Cell Proteomics. 2016 Aug;15(8):2576-93. doi: 10.1074/mcp.M116.058420. Epub 2016 May 16.
PMID: 27185884

2015

A competition between decapping complex formation and ubiquitin-mediated proteasomal degradation controls human Dcp2 decapping activity.
Erickson SL, Corpuz EO, Maloy JP, Fillman C, Webb K, Bennett EJ, Lykke-Andersen J.
Mol Cell Biol. 2015 Apr 13. pii: MCB.01517-14.
PMID: 25870104

The SCAR/WAVE complex polarizes PAN receptors and promotes division asymmetry in maize.
Facette MR, Park Y, Sutimantanapi D, Luo A, Cartwright HN, Yang B, Bennett EJ, Sylvester AW, Smith LG
Nature Plants 1, Article number: 14024 (2015) ?doi:10.1038/nplants.2014.24
Published online 26 January 2015

UnfoldedProteinThe Unfolded Protein Response Triggers Site-Specific Regulatory Ubiquitylation of 40S Ribosomal Proteins.
Higgins R, Gendron JM, Rising L, Mak R, Webb K, Kaiser SE, Zuzow N, Riviere P, Yang B, Fenech E, Tang X, Lindsay SA, Christianson JC, Hampton RY, Wasserman SA, Bennett EJ.
Mol Cell. 2015 Jun 3
PMID: 26051182

2014

6_10_15_bennett_lab_webpage_update003007Protecting the proteome: Eukaryotic cotranslational quality control pathways.
Lykke-Andersen J, Bennett EJ.
J Cell Biol. 2014 Feb 17;204(4):467-76.
PMID: 24535822

TIF1gamma Regulates Epithelial Mesenchymal Transition by Operating as a SUMO E3 Ligase for theTranscriptional Regulator SnoN1.
Ikeuchi Y, Dadakhujaev S, Chandhoke AS, Huynh MA, Oldenborg A, Ikeuchi M, Deng L, Bennett EJ, Harper JW, Bonni A, Bonni S.
J Biol Chem. 2014 Jul 24.
PMID: 25059663

Structural basis for translational surveillance by the large ribosomal subunit-associated protein quality control complex. 
Lyumkis D, Oliveira dos Passos D, Tahara EB, Webb K, Bennett EJ, Vinterbo S, Potter CS, Carragher B, Joazeiro CA.
Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):15981-6.
PMID: 25349383

2013

A novel Hap1-Tsc1 interaction regulates neuronal mTORC1 signaling and morphogenesis in the brain.
Mejia LA, Litterman N, Ikeuchi Y, de la Torre-Ubieta L, Bennett EJ, Zhang C, Harper JW, Bonni A.
J Neurosci. 2013 Nov 13;33(46):18015-21.
PMID: 24227713

Multimodal mechanism of action for the Cdc34 acidic loop: a case study for why ubiquitin-conjugating enzymes have loops and tails.
Ziemba A, Hill S, Sandoval D, Webb K, Bennett EJ, Kleiger G.
J Biol Chem. 2013 Nov 29;288(48):34882-96
PMID: 24129577

Parallel SCF Adaptor Capture Proteomics Reveals a Role for SCF(FBXL17) in NRF2 Activation via BACH1 Repressor Turnover. 
Tan MK, Lim HJ, Bennett EJ, Shi Y, Harper JW.
Mol Cell. 2013 Oct 10;52(1):9-24.
PMID: 24035498

The X-linked intellectual disability protein PHF6 associates with the PAF1 complex and regulates neuronal migration in the mammalian brain.
Zhang C, Mejia LA, Huang J, Valnegri P, Bennett EJ, Anckar J, Jahani-Asl A, Gallardo G, Ikeuchi Y, Yamada T, Rudnicki M, Harper JW, Bonni A.
Neuron. 2013 Jun 19;78(6):986-93.
PMID: 23791194

Using the ubiquitin modified proteome to monitor protein homeostasis function. 
Carrano AC, Bennett EJ.
Mol Cell Proteomics. 2013 May 23. [Epub ahead of print]
PMID: 23704779

Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes. 
Monda JK, Scott DC, Miller DJ, Lydeard J, King D, Harper JW, Bennett EJ, Schulman BA.
Structure. 2013 Jan 8;21(1):42-53.
PMID: 23201271

A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex.
Armour SM, Bennett EJ, Braun CR, Zhang XY, McMahon SB, Gygi SP, Harper JW, Sinclair DA.
Mol Cell Biol. 2013 Apr;33(8):1487-502.
PMID: 23382074

2012

Proteomics propels protein degradation studies in San Diego.
Bennett EJ, Mayor T.
Mol Cell Proteomics. 2012 Dec;11(12):1523-8.
PMID: 22798279

2011

Systematic and quantitative assessment of the ubiquitin modified proteome.
Kim, W.,* Bennett, E.J.*, Huttlin, E.L., Guo, A., Li, J., Possemato, A., Sowa, M.E., Rad, R., Rush, J., Comb, M.J., Harper, J.W., and Gygi, S.P.
Molecular Cell 2011 Oct 21;44(2):325-40.
PMID: 21906983
* Authors contributed equally

N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex. 
Scott, D.C., Monda, J.K., Bennett, E.J., Harper, J.W., Schulman, B.A.
Science 2011 Nov 4;334(6056): 674-8.
PMID: 21940857

Defining human ERAD networks through an integrative mapping strategy.
Christianson JC, Olzmann JA, Shaler TA, Sowa ME, Bennett EJ, Richter CM, Tyler RE, Greenblatt EJ, Wade Harper J, Kopito RR.
Nat Cell Biol. 2011 Nov 27. doi: 10.1038/ncb2383.
PMID: 22119785

Pre-2010

Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.
Bennett EJ, Bence NF, Jayakumar R, Kopito RR.
Molecular Cell 2005 Feb 4;17(3):351-365.
PMID: 15694337

Application and analysis of the GFPu family of ubiquitin-proteasome system reporters. 
Bence NF, Bennett EJ, Kopito RR.
Methods Enzymol. 2005;399:481-90.
PMID: 16338377

Global changes to the ubiquitin system in Huntington’s disease. 
Bennett EJ, Shaler TA, Woodman B, Ryu KY, Zaitseva TS, Becker CH, Bates GP, Schulman H, Kopito RR.
Nature 2007 Aug 9;448(7154):704-708.
PMID: 17687326

Defining the Human Deubiquitinating Enzyme Interaction Landscape. 
Sowa ME*, Bennett EJ*, Gygi SP, Harper JW.
Cell. 2009 Jul 23;138(2):389-403
*Authors contributed equally
PMID: 19615732

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